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Warfarin during pregnancy

Warfarin is an anticoagulant. It is used to prevent the formation of clots in heart disease or after heart surgery, especially after the surgical installation of a prosthetic heart valve.

How warfarin works

Warfarin works by blocking the action of vitamin K, a fat soluble compound that is necessary for blood clotting and is naturally found in fresh root vegetables, fruit, seeds, dairy products and meat.

Warfarin and pregnancy

Warfarin should not be taken during pregnancy because it may cause birth defects. Risks include bone and hand abnormalities, intrauterine growth retardation (IUGR), central nervous system abnormalities and eye abnormalities.

Warfarin passes into breastmilk and should not be used while breastfeeding.

Known food interactions

Warfarin blocks the anticoagulation properties of foods rich in vitamin K. These include:

  • broccoli
  • cabbage
  • cauliflower
  • kale
  • liver
  • spinach

Some foods also have anticlotting properties that can overpromote the effects of the drugs. Avoid foods such as:

  • vitamin E
  • fish oil supplements
  • foods rich in Omega-3 fatty acids

Alcohol may promote or diminish the effects of warfarin. Limit your alcohol intake to one drink a day while using the drug.

Disease interactions

Consult your doctor before taking this drug if you have a history of any of the following:

Drug interactions

Consult your doctor before taking warfarin if you are taking any of the following drugs, medications or supplements:

Reasons to consult your doctor

  • Contact your doctor immediately if you experience any of the following symptoms:
  • abnormal bleeding from the nose, gastrointestinal tract, urinary tract or uterus
  • allergic reaction including difficulty breathing
  • bleeding into skin and soft tissue
  • black vomit
  • bruising on the skin
  • excessive or unexpected menstrual bleeding
  • severe infection
  • swelling of the lips, tongue and throat
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