Antihistamines are used to treat the symptomatic relief of allergies and severe anaphylactic shock. Many antihistamines also have antiemetic properties, and are sometimes used to prevent vomiting from motion sickness, vertigo or the effects of chemotherapy.
There are a number of substances that can trigger the release of histamine and they range from pollen and insect bites to contact with certain metals. Some drugs such as penicillin type antibiotics, local anesthetics, morphine and all protein based drugs may also start a reaction.
Traditional antihistamines are sedative in nature and have been used to induce sleep. More modern antihistamines have removed this property. Although there are many antihistamines, three of the more common drugs are loratadine which is marketed as Claritin, fexofenadine which is sold as Allegra and diphenhydramine which can be found under many brand names including Benadryl.
Histamine is a natural substance released by the body when there is an allergic reaction causing sneezes, itching and rashes. Antihistamines are drugs of the H1-antagonist type that act against the effects of histamine.
There is no evidence to suggest that using antihistamines during pregnancy increases the risk of birth defects. If you are pregnant or are trying to conceive you should tell your doctor before taking antihistamines.
Common brand names
Diphenhydramine:
Fexofenadine:
Loratadine:
Common side effects of diphenhydramine
Do not use antihistamines while breastfeeeding. Loratadine and diphenhydramine both pass into the breastmilk and evidence suggests that fexofenadine may also be present.
Consult your doctor before giving antihistamines to infants and children since adverse reactions may be stronger.
There are no known food interactions.
Consuming alcohol in conjunction with diphenhydramine may increase the likelihood and severity of side effects and drowsiness.
Consult your doctor before taking this diphenhydramine if you have a history of any of the following:
Consult your doctor before taking diphenhydramine (see list of common brand names) if you are taking any of the following drugs, medications or supplements:
Consult your doctor before taking loratadine (Claritin) if you are taking any of the following drugs, medications or supplements:
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